Guide Chlamydia pneumoniae: The Lung and the Heart

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Articles

  1. Chlamydia pneumoniae
  2. Better Health Channel
  3. Chlamydial pneumonia - Clinicals, Diagnosis, and Management | Explain Medicine - Medical Joyworks
  4. MATERIALS AND METHODS

Fact Explanation Fever This is usually a low grade fever.

Chlamydophila pneumoniae, cause of heart disease?

This is due to endogenous pyrogens released in the inflammatory process. Fever This is usually a low grade fever. Tachycardia This is defined as heart rate Hypoxia, Fever, release of catecholamines causes increase in the heart rate. Tachypnoea Hypercarbia and Hypoxia stimulate respiratory center to increase the rate of respiration. Only few patients has this sign due to the mild nature of the disease. Pharyngeal erythema This is due to the inflammation of pharynx by the C.

Chlamydia pneumoniae

Erythema is a classic feature of acute inflammation. Cervical lymphadenopathy The local lymph nodes gets inflamed when the lymph is carrying the pathogens to the draining node.

This is a protective mechanism in infections. Coarse crackles They are generated by the opening of collapsed airways.

Better Health Channel

Usually these features are found in seriously ill patients. This sign can be a common finding but it doesn't prove the diagnosis. Rhonchi These can be heard diffusely in both sides. The sound is generated by the turbulent airflow in narrowed airways.


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Erythema multiforme These are polymorphous macular eruption , papules, and target lesions central bullae or vesicle with concentric rash. The lesions in the extremities can be observed. This can sometimes be associated with Chlamydia pneumonia. Ankle swelling, tenderness and erythema This is due to a reactive arthritis that can sometimes be associated with Chlamydia pneumonia.

Neck stiffness This is a feature of Meningoencephalitis- This is due to the spasm of neck muscles in passive flexion of the neck.

Chlamydial pneumonia - Clinicals, Diagnosis, and Management | Explain Medicine - Medical Joyworks

Papilloedema This is a feature of Meningoencephalitis- It indicates raised intracranial pressure due to cerebral oedema. Flaccid paralysis of the limbs with relative preservation of sensation This is a sign of complecated Chlamydia pneumonia Guillain Barre Syndrome Flaccid paralysis of the limbs with relative preservation of sensation This is a sign of complecated Chlamydia pneumonia Guillain Barre Syndrome Mitral regurgitation Myocarditis- Features of acute heart failure. Mitral regurgitation Myocarditis- Features of acute heart failure. Fine basal crepitations Myocarditis- Features of acute heart failure.

Investigations - Diagnosis. Fact Explanation Full blood count Can indicate granulocytosis but this is nonspecific.

Full blood count Can indicate granulocytosis but this is nonspecific. C-Reactive protein This is a acute response proteins and in is elevated in infections. Blood cultures, gram staining and antibiatogram This is done as a basic test to exclude other bacterial pathogens. There are irregular segmented inflammatory infiltrates. The commonest site is the middle or lower lobes chest X-ray This is done as a basic test to support clinical suspicion.

It can distinguish between antibodies in the IgM and IgG serum fractions,which helps in identifying recent from past infection and reinfection from primary infection. Serology C. However, they are insensitive for detection in direct smears. PCR Several C. An oropharyngial swab is used instead of sputum sample. Investigations - Management. Fact Explanation Chest X ray Done after 6 weeks to assess the state of resolving of the pneumonia. Chest X ray Done after 6 weeks to assess the state of resolving of the pneumonia.

Fact Explanation Decide the treatment setting Depends on severity-of-illness scores, assessed by the CURB criteria includes confusion, uremia, respiratory rate, low blood pressure and age 65 years or greater; each component carries one point.

Decide the treatment setting Depends on severity-of-illness scores, assessed by the CURB criteria includes confusion, uremia, respiratory rate, low blood pressure and age 65 years or greater; each component carries one point. Oxygen This is to improve oxygen saturation of the blood. Intravenous fluids Is given in hypotensive patients to replace volume depletion. Analgesia and antipyretics This improves well being of the patient. It helps to reduce pleuritic pain and improve breathing and sputum clearance.

Physiotherapy This is needed only if there is sputum retention Physiotherapy This is needed only if there is sputum retention Thromboprophylaxis with subcutaneous heparin and TED stockings This can be considered in patients hospitalized for more than 12hs. Thromboprophylaxis with subcutaneous heparin and TED stockings This can be considered in patients hospitalized for more than 12hs. Fact Explanation Tetracycline These are broad-spectrum antibiotics that inhibit protein synthesis of the pathogens. It is given mg four times daily for 14 days Tetracycline These are broad-spectrum antibiotics that inhibit protein synthesis of the pathogens.

It is given mg four times daily for 14 days Doxycycline These are broad-spectrum antibiotics that inhibit protein synthesis of the bacteria. It is given at a dose of mg twice daily for 14 days Doxycycline These are broad-spectrum antibiotics that inhibit protein synthesis of the bacteria.

MATERIALS AND METHODS

It is given at a dose of mg twice daily for 14 days Erythromycin This is a bactericidal drug. It is used as mg four times daily for 14 days. Erythromycin This is a bactericidal drug. Management of a patient with high mortality example: hospitalized patient with CURB 65 score over 3 This is empirical therapy. The rout of admission is by intravenous line. Intravenous antibiotics can be given to hospitalized patients CURB 65 score of 2 who can't take oral medications.

The Nagahama Study

Co-amoxiclav acts againsts gram positive organisms and gram negative cocci. It is resistant to beta lactamases. Clarythromycin has a bactericidal action. Ceftriaxone is a third generation cephalosporin and it they are broad-spectrum antibiotics with bactericidal action. Benzylpenicillin acts againsts gram positive organisms and gram negative cocci. Levofloxacin is a fluoroquinolone and it inhibits bacterial DNA synthesis.

It is Baceristatis. It has a more gram negative coverage. Concise, fact-based medical articles to refresh your knowledge Access a wealth of content and skim through a smartly presented catalog of diseases and conditions. References IMB Directory Join. Company About Team Jobs Contact. All rights reserved. This is due to pharyngitis caused by the pathogen Chlamydia pneumoniae. There is often a prolonged period of cough.